| HYPOTHYROIDISM CANINE | |
| Description | Primary Hypothyroidism in the dog can result from autoimmune lymphocytic thyroiditis, iodine deficiency or excess, thyroidal damage due to neoplasia or infection, or idiopathic thyroid atrophy. Secondary Hypothyroidism due to a deficiency of TSH secretion and Tertiary Hypothyroidism due to lack of effective TRH were also reported. There have been reports of concurrent Hypothyroidism and Hypoadrenocorticism (Polyglandular Syndrome). Congenital Hypothyroidism causing short limbs (dwarfism), a broad skull, skin changes, and in some cases goiter, macroglossia, or delayed dental eruption has been described in dogs. Polyneuropathy has been associated with hypothyroidism. |
| Species | Canine |
| Signs | Abdominal distention, Abnormal behavior, aggression, changing habits, Abnormal forelimb curvature, Abnormal forelimb reflexes, Abnormal hindlimb curvature, Abnormal hindlimb reflexes, Abnormal length estrus cycle, Abnormal length of estrus period, Abnormal proprioceptive positioning, Abnormal size testes/scrotum, Abnormal upper airway breathing sounds, Abortion or weak newborns, Alopecia, Anestrus, Anorexia, Arrhythmia, Ascites, Ataxia, Back atrophy, Blindness, Bradycardia, Buphthalmia, Change in voice, Circling, Cold skin, Coma, Corneal edema, opacity, Corneal ulcer, Deafness, Decreased amount of stools, absent feces, constipation, Decreased ecg voltages, Decreased hair, feather, pigment, Decreased or absent menace response but not blind, Decreased respiratory rate, Decreased tearing, lacrimation, Diarrhea, Disoriented, Dryness of skin or hair, Dullness, Dysmetria, Dysphagia, Dyspnea, Enophthalmos, Excessive or decreased sleeping, Excessive salivation, Exercise intolerance, Female infertility, First degree atrioventricular heart block, Forefoot pain, Forefoot swelling, Forelimb atrophy, Forelimb lameness, Forelimb pain, Forelimb swelling, Forelimb weakness, Galactorrhea, inappropriate milk production, Generalized lameness or stiffness, Generalized weakness, Head pressing, Head shaking, Head tilt, Head, face, ears, jaw weakness, droop, Head, face, ears, jaw, nose, nasal, swelling, Head, face, jaw, tongue atrophy, Head, face, neck, tongue hypoesthesia, Hemiparesis, Hepatosplenomegaly, Hindfoot pain, Hindfoot swelling, Hindlimb atrophy, Hindlimb lameness, Hindlimb pain, Hindlimb swelling, Hyperkeratosis, Hypertrichosis, too much hair or failure of shedding, Hypothermia, Inability to stand, Increased respiratory rate, Kyphosis, Lack of growth or weight gain, Lack of libido or erection, Male infertility, Mammary gland swelling, Muffled, decreased, heart sounds, Mummy, mummified fetus, Muscle hypotonia, Mydriasis, Neck swelling, Neck weakness, Neck, chest atrophy, Nystagmus, Oily skin, hair or feathers, greasy, Overweight, Pale, Paraparesis, Pelvic atrophy, Petechiae, ecchymoses, purpura, Pruritus, Ptosis, Pulse deficiency, Purulent, mucoid discharge, excess wax, foul odor, ears, Relative shortening forelimb, Relative shortening hind limb, Retained deciduous tooth, Retinal detachment, Rough hair coat, Rubbing ears, Seizures or syncope, Sinus arrhythmia, Skin crusts, Skin edema, Skin hyperpigmentation, Skin papules, Skin pustules, Skin scales, Skin vesicles, Small litter size, Strabismus, Tetraparesis, Tongue protrusion, Underweight, Vomiting or regurgitation, Weak pulse, Weakness of one hindlimb, Weight loss |
| References | Sieber-Ruckstuhl NS. Longitudinal assessment of thyroid function in dogs with hypoadrenocorticism: Clinical outcomes and prevalence of autoantibodies. J Vet Intern Med 2024 [https://doi.org/10.1111/jvim.17232] González KS. Clinical and magnetic resonance imaging findings in a French bulldog puppy with genetically confirmed congenital hypothyroidism. J Vet Intern Med 2024 [https://doi.org/10.1111/jvim.17029] Travail V. Assessment of the likelihood of hypothyroidism in dogs diagnosed with and treated for hypothyroidism at primary care practices: 102 cases (2016-2021). J Vet Intern Med 2024 [https://doi.org/10.1111/jvim.16993] Welle MM. Canine noninflammatory alopecia: An approach to its classification and a diagnostic aid. Vet Pathol 2023 [https://doi.org/10.1177/03009858231170295] Bugbee A. 2023 AAHA Selected Endocrinopathies of Dogs and Cats Guidelines. J Am Anim Hosp Assoc 2023 [https://doi.org/10.5326/JAAHA-MS-7368] Lathan P. Laboratory Diagnosis of Thyroid and Adrenal Disease. Vet Clin North Am Small Anim Pract 2023 [https://doi.org/10.1016/j.cvsm.2022.08.005] |